Lustig is a surname, and may refer to:

• Aaron Lustig (born 1956), American film and television actor
• Alessandro Lustig (1857–1937), Austro-Italian pathologist
• Alvin Lustig (1915–1955), American designer
• Arnošt Lustig (1926–2011), Czech Jewish author
• Billy Lustig (died 1913), American gang leader
• Bob Lustig, General Manager of the Buffalo Bills
• Branko Lustig (1932–2019), Croatian film producer
• main character in the fairy tale Brother Lustig
• Eugenia Sacerdote de Lustig (1910–2011), Argentine physician
• Fritz Lustig (1919–2017), German-Jewish emigrant to England during the Nazi era)
• Jo Lustig (1925–1999), American music entrepreneur
• John Lustig (born 1953), American comics writer
• Mikael Lustig (born 1986), Swedish footballer
• Nora Lustig, Argentinian professor of Latin American economics
• Peter Lustig (1937–2016), German television presenter and author of children's books
• Robin Lustig (born 1948), British radio broadcaster
• Robert H. Lustig, American professor of clinical pediatrics, expert on obesity and sugar
• Victor Lustig (1890–1947), Czech-born con artist
• William Lustig (born 1955), also known as Bill Lustig, American film director and producer